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Patients being treated in London hospitals were able to access pioneering clinical trials in greater numbers than ever before, it was revealed today.

A total of 152,269 people took part in research projects in the capital – up 19 per cent, or 24,004 participants, on the previous year. The number of studies increased five per cent, or 229, to 4,630.

The studies offer access to novel treatments ranging from cancer to stroke and Parkinson’s disease. While not all studies prove effective, many offer a last chance for patients left without other treatment options.

Guy’s and St Thomas’s topped the National Institute for Health Research annual research activity league table for the third year in a row in terms of the number of participants, 25,280. It hosted 500 studies, the highest in the capital and the third highest in the country.

Imperial College Healthcare, University College London Hospitals and Barts Health also featured in the national top 10 for the number of studies.

King’s College Hospital trust enrolled almost 21,000 patients – the fourth highest nationwide. The largest study at King’s, a world leader in fetal medicine, recruited nearly 8,500 patients to analyse cell-free DNA in maternal blood during the first three months of pregnancy.

Professor Charles Wolfe, director of research and development at Guy’s and St Thomas’ said: “We are extremely grateful to people in our local communities and beyond for partnering with us in such great numbers and helping us to lead the country for public and patient participation in research.”

Alero Dabor, a cancer survivor and patient research advocate at Guy’s and St Thomas’, said: “Patients and members of the public are increasingly being seen less as just participants and more as partners in research and this can only be a good thing.”